Wednesday, March 17th, 2010 at
11:52 pm
Amethyst asked:
my mom keeps getting these things on her arms that itch her and they bleed and then scab and she has a lot of them. she has lupus and i dunno if it’s from her lupus or if its a sign of skin cancer or not… cancer runs in my family. i’ve had 3 family members that i know of die of some kinda cancer and they were all on my mom’s side. and i’m very worried that it could be really bad.
Technorati Tags: Lot, Lupus, Mom
Monday, February 1st, 2010 at
12:08 pm

neminly asked: A lot of the teens on the skin care board are really using a lot of benzoyl peroxide. Should these products maybe state on the label or something that benzoyl peroxide is used to induce skin cancer in lab animals for skin cancer research?
http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&Cmd=ShowDetailView&TermToSearch=2507187&ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVAbstractPlus
Department of Dermatology Skin Diseases Research Center, University Hospitals of Cleveland, OH.
It is known that the free-radical-generating compound, benzoyl peroxide (BPO) enhances malignant conversion of murine skin benign papillomas into carcinomas.
If there is such a difference between rodent and human skin, why are they using the rodents to test skin cancer drugs for humans? What, the results of the drug tests are okay and helpful for humans but how we get it is different?
FDA MedWatch…
Benzoyl peroxide has been shown to be a tumor promoter and progression agent in a
number of animal studies. The clinical significance of this is unknown.
Benzoyl peroxide in acetone at doses of 5 and 10 mg administered twice per week induced
skin tumors in transgenic Tg.AC mice in a study using 20 weeks of topical treatment.
In a 52 week dermal photocarcinogenicity study in hairless mice, the median time to onset
of skin tumor formation was decreased and the number of tumors per mouse
increased following chronic concurrent topical administration of BenzaClin Topical Gel
with exposure to ultraviolet radiation (40 weeks of treatment followed by 12 weeks of
observation).
http://www.fda.gov/medwatch/SAFETY/2005/APR_PI/BenzaClin_PI.pdf
If it is used to turn benign papillomas (like a pimple) to malignant papillomas in lab animals at ONLY 5-10% applied ONLY 2 times a week from ONE source, How can the chem manufacturer state that it doesn’t?
Technorati Tags: Lot, Ncbi, Skin Cancer
Sunday, December 27th, 2009 at
8:52 am
bman6178 asked:
I am very frightened about getting this type of cancer. I am in the sun a lot and don’t usually wear sunscreen, where I live it is very hot and the sun is always out really. I do have freckles and I read that it might mean I have a better chance of getting skin cancer. What is the best way to prevent it?
Technorati Tags: Better Chance, Lot, Skin Cancer